What is licorice root good for?

Short answer: Licorice root has potential benefits for digestive health, cancer prevention and skin health.

Licorice root is taken from the licorice plant, scientifically known as glycyrrhiza glabra, which is native to the Middle East, Asia and parts of southern Europe.

The root of the licorice plant is known for its significant antioxidant, anti-inflammatory, and also antimicrobial properties, and has been used as a traditional medicine for millennia, dating as far back as ancient Egypt, for treating problems with the digestive tract.

Benefits for treating digestive issues


In present day, licorice root extract is often used to reduce the symptoms of acid reflux, heartburn, indigestion, and can even help treat peptic ulcers by increasing mucus production, reducing inflammation, and improving gut microbiome.

A two-year study that involved 58 adults diagnosed with gastroesophageal reflux disease (GERD) found that taking licorice root extract on a daily basis was even more effective at reducing symptoms than antacid medication.

Role in cancer prevention


Aside from its gastroprotective properties, licorice root extract is also being researched for its potential ability to reduce the risk of certain types of cancer, according to the National Cancer Institute. For example, some animal studies have demonstrated that licorice root extract helps slow or prevent cell growth in skin cancer, colorectal cancer, and breast cancer.

Role in skin health


Further research is also looking into licorice root extract's potential for treating skin conditions such as acne and eczema.

Deglycyrrhizinated licorice (DGL)


The active ingredient in licorice root is called glycyrrhizin, which is also responsible for its sweet taste, however glycyrrhizin is associated with some adverse side effects, which has led to some forms of licorice root supplements having the glycyrrhizin removed, resulting in what is known as deglycyrrhizinated licorice, often simply called DGL.

It is important to understand that DGL may not yield the same results as regular licorice root extract, given that a large amount of the anti-inflammatory and antioxidant properties observed in licorice root come specifically from the glycyrrhizin itself, although some studies have shown that DGL may be preferred over regular licorice extracts for treating and preventing ulcers.

Further research is definitely needed to distinguish the benefits and drawbacks between the two types of licorice root.

When should I take licorice root?

Short answer: Licorice root is best taken shortly before a meal, at any time of day.

Given their role in digestive health, licorice supplements are generally advised to be taken shortly before a meal for maximum benefit, in order to prime the gut for the digestive process.

Licorice is generally well tolerated at any time of day, and is even thought to be beneficial towards sleep if taken in the evening.



Licorice Root data sources & further reading


Last updated by Asklepios on 30th January, 2025

Remember

While every effort has been made to ensure that the above data is accurate, said accuracy can never be guaranteed. The information provided is not medical advice, it is not intended to cover all possible interactions or adverse effects, and neither is it a substitute for the expertise of professional healthcare practitioners. You are always encouraged to do your own research, and to consult with your trusted doctor or pharmacist before taking any supplements.


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