What is L-proline good for?

Short answer: L-proline has potential benefits for collagen production, skin health and wound healing.

L-proline is what is known as an amino acid, which means that it is used by the body as a building block for producing proteins. As the human body is capable of producing its own proline, it is not classified as an essential amino acid, however additional proline intake is important to ensure optimal protein production.

Role in collagen production


One of the most important proteins that L-proline is associated with is collagen, which serves as the framework for our skin, muscles, bones, tendons, cartilage, and other connective tissues, in addition to our organ membranes and artery walls. It is the most prevalent protein in the human body, and perhaps the most important.

For this reason, L-proline is often taken to promote skin health and enhance wound healing.

When should I take L-proline?

Short answer: L-proline is best taken on an empty stomach, at least 2 hours since the last meal and at least 30 minutes before the next meal.

As with most amino acids, L-proline is best taken between meals, on an empty stomach, in order to maximize bioavailability and absorption.

What does L-proline combine well with?

Short answer: L-Proline has been shown to work well together with L-lysine and vitamin C.

L-proline with L-lysine and vitamin C, for cardiovascular health


L-proline features prominently in Linus Pauling's heart health protocol, alongside L-lysine and vitamin C.

The idea is that L-lysine is tasked with dissolving atherosclerotic plaques that adhere to any damaged artery walls, while L-proline compliments vitamin C in the production of collagen necessary for rebuilding and repairing these artery walls and ensuring that they remain smooth, and free of any lesions for future plaque to adhere to.

What are natural sources of L-proline?

If you are interested in achieving your daily L-proline intake through your diet, rich sources of L-proline include:

  • Bone broth
  • Beef liver
  • Beef
  • Chicken
  • Salmon
  • Eggs
  • Cabbage
  • Asparagus
  • Peanuts
  • Legumes



L-Proline data sources & further reading


Last updated by Asklepios on 30th January, 2025

Remember

While every effort has been made to ensure that the above data is accurate, said accuracy can never be guaranteed. The information provided is not medical advice, it is not intended to cover all possible interactions or adverse effects, and neither is it a substitute for the expertise of professional healthcare practitioners. You are always encouraged to do your own research, and to consult with your trusted doctor or pharmacist before taking any supplements.


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